The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2026
Filed:
Mar. 29, 2019
Case Western Reserve University, Cleveland, OH (US);
University Hospitals Cleveland Medical Center, Cleveland, OH (US);
Agata Exner, Shaker Heights, OH (US);
Al De Leon, Cleveland, OH (US);
Reshani Perera, Twinsburg, OH (US);
Pinunta Nittayacharn, Cleveland, OH (US);
CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);
UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER, Cleveland, OH (US);
Abstract
A composition includes a plurality of stabilized nanobubbles and/or microbubbles. Each nanobubble and/or microbubble has a lipid membrane that defines at least one internal void, which includes at least one gas, the membrane including a plurality of lipids, an edge-activator, which is incorporated between lipids of the membrane and enhances the flexibility of the nanobubbles and/or microbubbles, and a membrane stiffener, which is incorporated on an outer surface of the membrane and enhances the membranes resistance to tearing.