The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2026

Filed:

Apr. 04, 2023
Applicants:

Shanghai Wei ER Biopharmaceutical Technology Co., Ltd., Shanghai, CN;

Shanghai Baolong Pharmaceutical Co., Ltd., Shanghai, CN;

Baolong Pharmaceutical Co., Ltd., Bozhou, CN;

Shanghai Baolong Anqing Pharmaceutical Co., Ltd., Anqing, CN;

Inventors:

Xin Wu, Shanghai, CN;

Youfa Xu, Shanghai, CN;

Zhizhe Lin, Shanghai, CN;

Yongjie Huang, Shanghai, CN;

Jianming Chen, Shanghai, CN;

Yuansheng Zhang, Shanghai, CN;

Zhiqin Fu, Shanghai, CN;

Xinmei Chen, Shanghai, CN;

Hang Chen, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4422 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 47/10 (2017.01); A61K 47/40 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4422 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 47/10 (2013.01); A61K 47/40 (2013.01);
Abstract

The present invention relates to the technical field of pharmaceutics, and in particular, to a safe and stable nimodipine formulation for injection and a method for preparing same. The present invention provides a lyophilized nimodipine-cyclodextrin powder for injection, comprising sulfobutylether-β-cyclodextrin, which can significantly improve the solubility, safety, and dilution stability of nimodipine, and increase patient compliance and the convenience of clinical use. Compared with a commercially available nimodipine injection NIMOTOP, the present invention has significant advantages in safety and dilution stability.


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