The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2026
Filed:
Jun. 11, 2020
Applicant:
Hadasit Medical Research Services and Development Ltd., Jerusalem, IL;
Inventors:
Benjamin Eithan Reubinoff, Moshav Bar-Giora, IL;
Etti Ben-Shushan, Jerusalem, IL;
Assignee:
Hadasit Medical Research Services and Development Ltd., Jerusalem, IL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/166 (2006.01); A61P 9/10 (2006.01); A61P 25/28 (2006.01); A61P 37/06 (2006.01); C12N 5/079 (2010.01);
U.S. Cl.
CPC ...
A61K 31/166 (2013.01); A61P 9/10 (2018.01); A61P 25/28 (2018.01); A61P 37/06 (2018.01); C12N 5/0622 (2013.01); C12N 2500/02 (2013.01); C12N 2501/105 (2013.01); C12N 2501/115 (2013.01); C12N 2501/33 (2013.01); C12N 2506/02 (2013.01);
Abstract
A method of generating human mature oligodendrocytes is disclosed. The method comprises contacting a cell population which comprises human pre-oligodendrocytes with an inhibitor of the MAPK/ERK pathway under conditions that allow the pre-oligodendrocytes to differentiate into mature oligodendrocytes. Use of the MAPK/ERK pathway inhibitor for treating diseases is also disclosed.