The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2026
Filed:
Nov. 25, 2021
Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, CN;
Ascentage Pharma Group Corp Limited, Admiralty, HK;
Yanqiong Lin, Suzhou, CN;
Hualiang Xu, Suzhou, CN;
Feng Xu, Suzhou, CN;
Chen Wu, Suzhou, CN;
Hongtao Guo, Suzhou, CN;
Xiaoling He, Suzhou, CN;
ASCENTAGE PHARMA (SUZHOU) CO., LTD., Suzhou, CN;
ASCENTAGE PHARMA GROUP CORP LIMITED, Hong Kong, CN;
Abstract
The invention discloses a solid dispersion, a pharmaceutical preparation, a preparation method and an application thereof. The solid dispersion of the invention comprises carriers and active constituents, which is a compound as shown in formula (I) and/or a pharmaceutically acceptable salt thereof; The carrier is “homopolymer and copolymer of N-vinyl lactam” and/or pH-dependent cellulose derivatives. The preparation of the invention comprises the solid dispersion, fillers and disintegrating agents. The solid dispersion of the invention has good dissolution and significantly improves the solubility of effective constituents. The preparation can effectively improve the bioavailability of Bcl-2 inhibitor, has good dissolution and stability, and can improve the safety of a medication.