The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2026
Filed:
Oct. 23, 2018
Applicants:
The Broad Institute, Inc., Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Feng Zhang, Cambridge, MA (US);
Jonathan Gootenberg, Cambridge, MA (US);
David Benjamin Turitz Cox, Cambridge, MA (US);
Omar Abudayyeh, Cambridge, MA (US);
Ian Slaymaker, Cambridge, MA (US);
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 9/50 (2006.01); A61P 43/00 (2006.01); C12N 9/78 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); A61K 9/50 (2013.01); A61P 43/00 (2018.01); C12N 9/78 (2013.01); C12N 15/11 (2013.01); C12Y 305/04004 (2013.01); C12Y 305/04005 (2013.01); C12N 2310/20 (2017.05); C12N 2320/32 (2013.01); C12N 2800/80 (2013.01);
Abstract
The present disclosure provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the present disclosure provides non-naturally occurring or engineered RNA-targeting systems comprising a RNA-targeting Cas13 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof.