The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2026

Filed:

Sep. 16, 2021
Applicants:

The Regents of the University of California, Oakland, CA (US);

Coopervision International Limited, Fareham, GB;

Inventors:

Alireza Khademhosseini, Los Angeles, CA (US);

Shiming Zhang, Hong Kong, CN;

Sourav Saha, Pleasanton, CA (US);

Mehmet R. Dokmeci, Los Angeles, CA (US);

Lu Jiang, Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/145 (2006.01); A61B 5/1477 (2006.01); A61F 9/00 (2006.01); B29D 11/00 (2006.01); C08J 3/075 (2006.01); G02B 1/04 (2006.01); G02C 7/04 (2006.01); B29K 33/00 (2006.01); B29K 105/00 (2006.01);
U.S. Cl.
CPC ...
C08J 3/075 (2013.01); A61B 5/14507 (2013.01); A61B 5/14546 (2013.01); A61B 5/1477 (2013.01); A61F 9/0017 (2013.01); B29D 11/00048 (2013.01); B29D 11/00096 (2013.01); G02B 1/043 (2013.01); G02C 7/049 (2013.01); B29K 2033/12 (2013.01); B29K 2105/0061 (2013.01); C08J 2333/10 (2013.01); C08J 2481/08 (2013.01);
Abstract

Microchannels in hydrogels play an essential role in enabling a smart contact lens. A wearable contact lens is disclosed herein that uses microchannels and connected chambers located in poly-2-hydroxyethyl methacrylate (poly(HEMA)) hydrogel that is used in a commercial contact lens with three-dimensional (3D) printed mold. The corresponding capillary flow behaviors in these microchannels were investigated. Different capillary flow regimes were observed in these microchannels, depending on the hydration level of the hydrogel material. In particular, it was found that a peristaltic pressure could reinstate flow in a dehydrated microchannel, indicating the motion of eye-blinking may help tear flow in a microchannel-containing contact lens. Colorimetric pH and electrochemical Nasensing capabilities were demonstrated in these microchannels. Micro-engineered contact lenses formed using poly(HEMA) hydrogel can be used for various biomedical applications such as eye-care and wearable biosensing.


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