The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2026
Filed:
Aug. 09, 2021
Applicant:
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Inventors:
Martin D. Burke, Champaign, IL (US);
Arun Maji, Champaign, IL (US);
Assignee:
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 17/08 (2006.01); A61P 31/10 (2006.01);
U.S. Cl.
CPC ...
C07H 17/08 (2013.01); A61P 31/10 (2018.01);
Abstract
Disclosed are C16 amide derivatives of C2'-epi-amphotericin B (C2′epiAmB) and salts thereof, characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions, comprising any of the disclosed compounds or salts thereof, as well as methods of treatment and therapeutic uses of the same.