The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2026

Filed:

Sep. 28, 2021
Applicant:

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Pudong Shanghai, CN;

Inventors:

Huaqiang Xu, Pudong Shanghai, CN;

Jia Li, Pudong Shanghai, CN;

Jingjing Shi, Pudong Shanghai, CN;

Yi Zang, Pudong Shanghai, CN;

Dandan Sun, Pudong Shanghai, CN;

Mingliang Liu, Pudong Shanghai, CN;

Rongrong Xie, Pudong Shanghai, CN;

Erli You, Pudong Shanghai, CN;

Lixin Gao, Pudong Shanghai, CN;

Qian Tan, Pudong Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61K 31/46 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 471/08 (2013.01);
Abstract

A strong FXR small-molecule agonist, and a preparation method therefor and use thereof, the structure of the agonist being represented by formula (I), are provided. In the formula, each substituent is as defined in the description and the claims. The compound provided has the advantages of high FXR agonist activity, simple synthesis, easily available raw materials and the like, and can be used for preparing medicines for treating FXR related diseases.


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