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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12655095 B1

PDFFull Text
Date of Patent:
Jun. 16, 2026

Filed:

Sep. 22, 2021

Tes-based cationic lipids

Applicant:

Translate Bio, Inc., Waltham, MA (US);

Inventors:

Shrirang Karve, Acton, MA (US);

Frank Derosa, Chelmsford, MA (US);

Assignee:

TRANSLATE BIO, INC., Waltham, MA (US);

Attorneys:

LATHROP GPM LLP

James H. Velema, Esq.

Primary Examiner:

Yate′ K Cutliff

Int. Cl.
CPC ...
C07C 311/32 (2006.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 9/1271 (2025.01); A61K 48/00 (2006.01); C07C 309/69 (2006.01); C07C 311/34 (2006.01);
U.S. Cl.
CPC ...
C07C 311/32 (2013.01); A61K 9/007 (2013.01); A61K 9/1075 (2013.01); A61K 9/1271 (2013.01); A61K 48/0033 (2013.01); C07C 309/69 (2013.01); C07C 311/34 (2013.01);
Abstract

The present invention provides, in part, TES-based lipid compounds of Formula (Ia), and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.

Find Patent Forward Citations

Karve, Shrirang. (2026). Tes-based cationic lipids (U.S. Patent No. 12655095). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12655095

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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