The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2026
Filed:
Sep. 26, 2019
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Nathanael S. Gray, Boston, MA (US);
Baishan Jiang, Brookline, MA (US);
Behnam Nabet, Boston, MA (US);
Tinghu Zhang, Brookline, MA (US);
Mingfeng Hao, Hefei, CN;
Assignee:
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 47/54 (2017.01); A61K 47/55 (2017.01); C07D 401/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
A61K 47/55 (2017.08); A61K 47/545 (2017.08); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 417/14 (2013.01);
Abstract
Disclosed are bifunctional compounds (degraders) that target FAK or FAK and ALK for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat disease.