The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2026

Filed:

Sep. 11, 2020
Applicant:

Impact Therapeutics (Shanghai), Inc, Shanghai, CN;

Inventors:

Sui Xiong Cai, Shanghai, CN;

Ye Edward Tian, Shanghai, CN;

Xiaozhu Wang, Nanjing, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/4745 (2006.01); A61K 31/4985 (2006.01); A61P 35/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/4745 (2013.01); A61K 31/4985 (2013.01); A61P 35/00 (2018.01); C07D 487/04 (2013.01);
Abstract

The disclosure provides substituted imidazo[1,5-a]quinoxaline and related compounds as kinase inhibitors, and their uses. Specifically, the disclosure provides compounds of Formula I, or pharmaceutically acceptable salts thereof or prodrugs thereof, wherein, A-A, Cy and R-Rare defined herein. The compounds of Formula I are kinase inhibitors. Therefore, the compounds of the disclosure can be used to treat clinical conditions caused by DDR function defects, such as cancers.


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