The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2026
Filed:
May. 26, 2021
Jiangsu Yahong Meditech Co., Ltd., Taizhou, CN;
Asieris Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, CN;
Jianghua Liu, Taizhou, CN;
Ke Pan, Shanghai, CN;
Yushen Guo, Shanghai, CN;
Shuai Shen, Taizhou, CN;
Jili Sun, Taizhou, CN;
Dandan Li, Taizhou, CN;
Jie Chen, Taizhou, CN;
Jiangsu Yahong Meditech Co., Ltd., Taizhou, CN;
Asieris Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, CN;
Abstract
Pharmaceutical compositions comprising nitroxoline lysinate, a preparation method therefor and a use thereof. The pharmaceutical compositions comprise a first layer and a second layer. The first layer comprises, based on the total weight of the first layer, 40%-70% of active pharmaceutical ingredient, 10%-30% of filler, 5%-12% of disintegrant, 0.5%-2% of lubricant, 0.1%-1.5% of glidant and 10%-20% of alkaline substance. The second layer comprises, based on the total weight of the second layer, 40%-70% of active pharmaceutical ingredient, 10%-30% of filler, 10%-35% of sustained-release material, 0.1%-2% of lubricant and 0.1%-2% of glidant. The active pharmaceutical ingredient is selected from one or more of nitroxoline lysinate, nitroxoline lysinate crystalline form and nitroxoline lysinate solvate. The pharmaceutical compositions can achieve the purpose of burst release at an early stage and sustained and slow release at a later stage.