The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2026
Filed:
Mar. 10, 2021
Applicant:
Jmackem Co., Ltd, Seoul, KR;
Inventors:
Jeewoo Lee, Seoul, KR;
Jihyae Ann, Seoul, KR;
Assignee:
JMACKEM CO., LTD, Seoul, KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4545 (2006.01); A23L 33/10 (2016.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 31/07 (2006.01); A61K 31/197 (2006.01); A61K 31/355 (2006.01); A61K 31/375 (2006.01); A61K 31/4184 (2006.01); A61K 31/4188 (2006.01); A61K 31/427 (2006.01); A61K 31/4415 (2006.01); A61K 31/4439 (2006.01); A61K 31/455 (2006.01); A61K 31/519 (2006.01); A61K 31/525 (2006.01); A61K 31/5377 (2006.01); A61K 31/714 (2006.01); A61K 33/00 (2006.01); A61K 33/06 (2006.01); A61K 33/10 (2006.01); A61K 33/26 (2006.01); A61K 33/30 (2006.01); A61K 47/02 (2006.01); A61K 47/26 (2006.01); A61P 29/00 (2006.01); C07D 235/26 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4545 (2013.01); A23L 33/10 (2016.08); A61K 9/0053 (2013.01); A61K 9/0095 (2013.01); A61K 9/08 (2013.01); A61K 9/1623 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2059 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01); A61K 31/07 (2013.01); A61K 31/197 (2013.01); A61K 31/355 (2013.01); A61K 31/375 (2013.01); A61K 31/4184 (2013.01); A61K 31/4188 (2013.01); A61K 31/427 (2013.01); A61K 31/4415 (2013.01); A61K 31/4439 (2013.01); A61K 31/455 (2013.01); A61K 31/519 (2013.01); A61K 31/525 (2013.01); A61K 31/5377 (2013.01); A61K 31/714 (2013.01); A61K 33/00 (2013.01); A61K 33/06 (2013.01); A61K 33/10 (2013.01); A61K 33/26 (2013.01); A61K 33/30 (2013.01); A61K 47/02 (2013.01); A61K 47/26 (2013.01); A61P 29/00 (2018.01); C07D 235/26 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); A23V 2002/00 (2013.01);
Abstract
The present invention relates to a benzimidazolone-based cinnamamide derivative as a TRPV1 antagonist and a pharmaceutical composition for treating or preventing pain containing the same as an active ingredient. The example compounds provided in one aspect of the present invention block the TRPV1 activation caused by capsaicin, a TRPV1 receptor activator, but induce an appropriate inhibition of about 20% to 80% of pH, thereby the compounds have effects of alleviating pain and effectively reducing side effects such as abnormal body temperature.