The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2026
Filed:
Nov. 14, 2022
Gwo Xi Stem Cell Applied Technology Co., Ltd., Zhubei, TW;
Wei Wu Li, Zhubei, TW;
Tzyy-Wen Chiou, Zhubei, TW;
Horng-Jyh Harn, Zhubei, TW;
Shinn-Zong Lin, Zhubei, TW;
Ming-Hsi Chuang, Zhubei, TW;
PO-Cheng Lin, Zhubei, TW;
Chia-Hsin Lee, Zhubei, TW;
Mao-Hsuan Huang, Zhubei, TW;
Gwo Xi Stem Cell Applied Technology Co., Ltd., Zhubei, TW;
Abstract
The present invention provides a medicine for treating a neurodegenerative disease, which employs LEFTY2 (Left-Right Determination Factor 2) generated by co-culturing mesenchymal stem cells of mammals with nerve cells having mutations in the APP (Amyloid precursor protein) gene, or a specific protein. The LEFTY2 has an effect of inhibiting Beta amyloid and a hyperphosphorylated neuronal microtubule-associated protein (Tau protein), without affecting the development of nerve cells and having the ability to promote the growth of the nerve cells; and the two types of proteins have a crucial impact on the neurodegenerative diseases.