The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2026

Filed:

Sep. 25, 2019
Applicant:

Ascendis Pharma A/s, Hellerup, DK;

Inventors:

Kennett Sprogøe, Hellerup, DK;

Sebastian Stark, Heidelberg, DE;

Tobias Voigt, Heidelberg, DE;

Lars Holten-Andersen, Hellerup, DK;

Nicola Bisek, Heidelberg, DE;

Assignee:

ASCENDIS PHARMA A/S, Hellerup, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/00 (2006.01); A61K 9/00 (2006.01); A61K 9/46 (2006.01); A61K 31/06 (2006.01); A61K 31/74 (2006.01); A61K 31/765 (2006.01); A61K 38/12 (2006.01); A61K 47/60 (2017.01); A61K 47/64 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 9/0007 (2013.01); A61K 9/0019 (2013.01); A61K 9/0024 (2013.01); A61K 31/06 (2013.01); A61K 31/74 (2013.01); A61K 31/765 (2013.01); A61K 38/12 (2013.01); A61K 47/645 (2017.08); A61K 47/6903 (2017.08);
Abstract

The present invention relates among other aspects to a conjugate or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising said conjugate or its pharmaceutically acceptable salt for use in a method of preventing or treating an infection, wherein said conjugate is water-insoluble and comprises a polymeric moiety —Z to which a plurality of moieties -L-X-L-D are covalently conjugated, wherein each -D is independently an antibiotic moiety; each -L- is independently a linker moiety to which -D is covalently and reversibly conjugated; each —X— is independently absent or a linkage and each -L- is independently either a chemical bond or a spacer moiety.


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