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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12648908 B1

PDFFull Text
Date of Patent:
Jun. 09, 2026

Filed:

Apr. 01, 2022

Cationic lipid, liposome containing cationic lipid, and nucleic-acid pharmaceutical composition containing liposome and formulation and application thereof

Applicant:

Xiamen Sinopeg Biotech Co., Ltd., Xiamen, CN;

Inventors:

Wengui Weng, Xiamen, CN;

Chao Liu, Xiamen, CN;

Ailan Wang, Xiamen, CN;

Sheng Lin, Xiamen, CN;

Assignee:

XIAMEN SINOPEG BIOTECH CO., LTD., Xiamen, CN;

Attorney:

Oliff PLC

Primary Examiner:

Sikarl A Witherspoon

Int. Cl.
CPC ...
C07C 219/06 (2006.01); A61K 9/1272 (2025.01); A61K 9/51 (2006.01); A61K 45/06 (2006.01); C07C 229/16 (2006.01); C07C 229/26 (2006.01); C07C 271/16 (2006.01); C07C 271/18 (2006.01); C07D 207/452 (2006.01); C07D 233/60 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 9/1272 (2013.01); A61K 9/5123 (2013.01); A61K 45/06 (2013.01); C07C 219/06 (2013.01); C07C 229/16 (2013.01); C07C 229/26 (2013.01); C07C 271/16 (2013.01); C07C 271/18 (2013.01); C07D 207/452 (2013.01); C07D 233/60 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01);
Abstract

A novel cationic lipid has a structure as represented by general formula (1) and specifically relates to a nitrogen-branched cationic lipid, and a liposome containing the cationic lipid, and a nucleic-acid pharmaceutical composition containing the liposome, a preparation method and application thereof, wherein, the definition of each symbol in the formula (1) is as defined herein. The cationic liposome containing the cationic lipid as represented by formula (1) can improve the loading rate and transport efficiency of nucleic-acid drugs. The formulation of the cationic liposome nucleic-acid pharmaceutical composition has good cell compatibility and higher gene transfection capability, and can improve the treatment and/or prevention effects of nucleic-acid drugs.

Find Patent Forward Citations

Weng, Wengui. (2026). Cationic lipid, liposome containing cationic lipid, and nucleic-acid pharmaceutical composition containing liposome and formulation and application thereof (U.S. Patent No. 12648908). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12648908

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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