The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2026

Filed:

Dec. 02, 2024
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Feng Zhang, Cambridge, MA (US);

Ian Slaymaker, Cambridge, MA (US);

Soumya Kannan, Cambridge, MA (US);

Jonathan Gootenberg, Cambridge, MA (US);

Omar Abudayyeh, Cambridge, MA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 38/46 (2006.01); A61K 38/50 (2006.01); C12N 9/78 (2006.01); C12N 15/11 (2006.01); C12N 15/55 (2006.01); C12N 15/62 (2006.01); C12Q 1/6823 (2018.01); C12Q 1/6851 (2018.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/78 (2013.01); C12N 9/22 (2013.01); C12N 15/111 (2013.01); C12Q 1/6823 (2013.01); C12Q 1/6851 (2013.01); A61K 38/00 (2013.01); C07K 2319/33 (2013.01); C12N 2310/128 (2013.01); C12N 2310/16 (2013.01); C12N 2310/20 (2017.05); C12Y 305/04004 (2013.01);
Abstract

The present disclosure provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides mutated Cas13 proteins and their use in modifying target sequences as well as mutated Cas13 nucleic acid sequences and vectors encoding mutated Cas13 proteins and vector systems or CRISPR-Cas13 systems.


Find Patent Forward Citations

Loading…