The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2026
Filed:
Dec. 20, 2022
Applicant:
2seventy Bio, Inc., Cambridge, MA (US);
Inventor:
Kevin Friedman, Melrose, MA (US);
Assignee:
2seventy bio, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 35/17 (2025.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4215 (2025.01); C07K 14/7051 (2013.01); C07K 16/2878 (2013.01); A61K 2239/38 (2023.05); A61K 2239/46 (2023.05); A61K 2239/48 (2023.05); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/74 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/51 (2013.01); C12N 2501/515 (2013.01); C12N 2501/599 (2013.01); C12N 2501/727 (2013.01); C12N 2501/999 (2013.01); C12N 2510/00 (2013.01);
Abstract
The invention provides improved T cell compositions and methods for manufacturing T cells. More particularly, the invention provides methods of T cell manufacturing that result in adoptive T cell immunotherapies with improved survival, expansion, and persistence in vivo.