The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2026
Filed:
May. 04, 2023
Applicant:
Scinopharm Taiwan, Ltd., Tainan, TW;
Inventors:
Assignee:
SCINOPHARM TAIWAN, LTD., Tainan, TW;
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); C07D 333/38 (2006.01); C07D 409/12 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); C07D 333/38 (2013.01); C07D 409/12 (2013.01);
Abstract
The present disclosure provides improved processes for the preparation of Relugolix and intermediates thereof. Relugolix is prepared via intermediates (M7) and (M8): wherein X is as described herein. Present disclosure also provides three additional routes to prepare Relugolix and intermediates thereof, where the starting material of ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate (SM1) is protected by coupling with an acyl chloride, a hydroxylamine or an oxime.