The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2026

Filed:

May. 17, 2023
Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Joanna L. Chen, Newton, MA (US);

Yi-Heng Chen, Whippany, NJ (US);

Erin F. Dimauro, Cambridge, MA (US);

Min Lu, Brookline, MA (US);

Joey L. Methot, Westwood, MA (US);

Andrew J. Musacchio, Westborough, MA (US);

Anandan Palani, Needham, MA (US);

Barbara Pio, West Orange, NJ (US);

Lorena Rico Duque, Canton, MA (US);

Phieng Siliphaivanh, Newton, MA (US);

Brandon A. Vara, Boston, MA (US);

Xavier Fradera, Boston, MA (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/4196 (2006.01); A61K 31/429 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/497 (2006.01); A61K 31/5383 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4196 (2013.01); A61K 31/429 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/497 (2013.01); A61K 31/5383 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01);
Abstract

Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as RIPK1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for RIPK1-related diseases.


Find Patent Forward Citations

Loading…