The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2026

Filed:

Dec. 14, 2020
Applicant:

Tongji University, Shanghai, CN;

Inventors:

Yihan Chen, Shanghai, CN;

Dandan Liang, Shanghai, CN;

Yi Liu, Shanghai, CN;

Subas Man Sakya, Shanghai, CN;

Xiang Li, Shanghai, CN;

Li Li, Shanghai, CN;

Huixing Zhou, Shanghai, CN;

Fulei Zhang, Shanghai, CN;

Xiaoyu He, Shanghai, CN;

Jinhua Yang, Shanghai, CN;

Assignee:

Tongji University, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/06 (2006.01); A61P 9/10 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 405/14 (2006.01); C07D 409/06 (2006.01); C07D 413/06 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C07D 405/06 (2013.01); A61P 9/10 (2018.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 405/14 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01); C12N 5/0657 (2013.01);
Abstract

Provided are novel heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases. Specifically, provided are the compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs, preparation method thereof, application thereof and pharmaceutical composition useful for treatment of heart diseases.


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