The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2026

Filed:

Sep. 23, 2022
Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Shaoqin Gong, Middleton, WI (US);

Ruosen Xie, Madison, WI (US);

Dai Yamanouchi, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 24/04 (2006.01); A61L 24/00 (2006.01); A61L 24/02 (2006.01);
U.S. Cl.
CPC ...
A61L 24/043 (2013.01); A61L 24/0031 (2013.01); A61L 24/02 (2013.01); A61L 2400/04 (2013.01);
Abstract

The present technology provides a composition comprising a mixture of a source of calcium ions, alginate conjugated to an acrylate monomer (ALG-A), carboxymethylcellulose conjugated to an acrylate monomer (CMC-A) and water, wherein the mixture is a shear-thinning gel. The compositions may further include a polythiol agent. Such compositions are injectable due to their shear-thinning properties, yet stay in place, undergo in situ crosslinking, and provide safe, simple and efficacious endovascular embolization. Methods of making and using such compositions are also provided.


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