The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2026
Filed:
Apr. 08, 2020
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Nathanael Gray, Boston, MA (US);
Inchul You, Boston, MA (US);
Tinghu Zhang, Brookline, MA (US);
Eric Fischer, Chestnut Hill, MA (US);
Katherine Donovan, Boston, MA (US);
Emily Erickson, Brookline, MA (US);
Alex Toker, Dedham, MA (US);
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
BETH ISRAEL DEACONESS MEDICAL CENTER, INC., Boston, MA (US);
Abstract
Bifunctional compounds comprising a GDC-0068 analog that binds AKT isoforms AKT1, 2 and 3 and a degron which represents a moiety that binds an E3 ubiquitin ligase, covalently attached to each other by a linker, pharmaceutical compositions, and methods for treating diseases or conditions mediated by dysfunctional AKT activity.