The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2026
Filed:
Dec. 01, 2022
Applicants:
Visterra, Inc., Waltham, MA (US);
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Inventors:
Gregory Babcock, Marlborough, MA (US);
Wayne Hancock, Philadelphia, PA (US);
Assignees:
Visterra, Inc., Waltham, MA (US);
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 31/436 (2006.01); A61P 37/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2013 (2013.01); A61K 31/436 (2013.01); A61P 37/06 (2018.01);
Abstract
The present invention provides, among other things, methods of using IL-2 fusion proteins, comprising an IL-2 variant and an Pc region, to treat and/or prevent heart transplant rejections. Methods of treating heart disease or a symptom thereof, conditioning a subject for heart transplant, modulating immunosuppression, and selectively increasing regulatory T cells are also disclosed.