The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2026

Filed:

May. 29, 2020
Applicants:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Université DE Pau ET Des Pays DE L'adour, Pau, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Laurent Billon, St. Faust, FR;

Eva Dieuzy, Seyssinet-Pariset, FR;

Garbine Aguirre, Lons, FR;

Solange Massa, Palo Alto, CA (US);

Peter Luke Santa Maria, Redwood City, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 9/06 (2006.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1808 (2013.01); A61K 9/06 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01);
Abstract

Mucoadhesive microgel compositions, which include an active agent (such as HB-EGF), are provided. Aspects of the invention include a microgel comprising a crosslinked poly(ethylene glycol) methyl ether methacrylate polymer comprising a mucoadhesive functionality. Also provided are methods of making and using the mucoadhesive microgel compositions, e.g., in therapeutic applications. In one embodiment, HB-EGF loaded mucoadhesive microgel compositions are provided, e.g., for prevention or treatment of mucositis conditions, such as therapy induced oral mucositis conditions.


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