The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2026

Filed:

Oct. 17, 2018
Applicants:

Apeliotus Technologies, Inc., Philadelphia, PA (US);

Massachusetts Eye and Ear Infirmary, Boston, MA (US);

Inventors:

John G. Edwards, Philadelphia, PA (US);

Joan W. Miller, Winchester, MA (US);

Demetrios Vavvas, Boston, MA (US);

Assignees:

APELIOTUS TECHNOLOGIES, INC., Philadelphia, PA (US);

MASSACHUSETTS EYE AND EAR INFIRMARY, Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G16H 10/20 (2018.01); A61B 3/06 (2006.01); A61B 3/10 (2006.01); A61B 5/00 (2006.01); A61K 31/40 (2006.01);
U.S. Cl.
CPC ...
G16H 10/20 (2018.01); A61B 3/063 (2013.01); A61B 3/102 (2013.01); A61B 5/4848 (2013.01); A61K 31/40 (2013.01);
Abstract

Methods of using visual functions such as dark adaptation, low luminance visual acuity, low luminance deficit, contrast sensitivity and scotopic sensitivity as functional biomarkers for statin therapy in AMD. These biomarkers can be used, for example, to support clinical trials of statin therapy for AMD by identifying participants more likely to respond, by providing an early indication of response, or by serving as an endpoint; or to support treatment of AMD patients with statins by identifying patients more likely to respond, by providing an early indication of responders vs. non-responders, or by confirming a treatment benefit.


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