The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2026

Filed:

Nov. 16, 2023
Applicant:

Cfd Research Corporation, Huntsville, AL (US);

Inventors:

Carrie Lynn German, Huntsville, AL (US);

Balabhaskar Prabhakarpandian, Madison, AL (US);

Ketan Harendrakumar Bhatt, Huntsville, AL (US);

Ashley Gilbert Helser, Huntsville, AL (US);

Assignee:

CFD RESEARCH CORPORATION, Huntsville, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G09B 23/28 (2006.01); G09B 23/30 (2006.01);
U.S. Cl.
CPC ...
G09B 23/281 (2013.01); G09B 23/303 (2013.01);
Abstract

The method involves computationally modeling a placenta by simulating physical placenta models with computational in silico models. The simulated data is compared with actual data from the physical models, and the simulation is iterated until a match is achieved. The method may also include calibrating diffusion parameters for testing substances, and configuring the models for analyzing instances of fluid-induced shear and substance transport. The simulated data may be used to obtain maternal-fetal pharmacokinetic in silico placenta models, and the method may be used to obtain predictions for time-dependent concentrations of molecules in fetal circulation. The computational models may consider instances of fluid-diffusive transport and carrier-mediated transport in calculations and determinations of transport characteristics and values of different testing substances.


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