The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2026

Filed:

Sep. 23, 2020
Applicants:

Assistance Publique-hopitaux DE Paris, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale, Paris, FR;

Université DE Reims Champagne-ardenne, Reims, FR;

Universite Paris Cite, Paris, FR;

Inventors:

François Rannou, Paris, FR;

Amanda Robinson, Le Kremlin-Bicêtre, FR;

Didier Borderie, Paris, FR;

François Etienne, Rouen, FR;

Cyril Gobinet, Athies-sous-Laon, FR;

Christelle Nguyen, Paris, FR;

Claire Mangeney, Villejuif, FR;

Olivier Piot, Cormontreuil, FR;

Attorney:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 21/65 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6887 (2013.01); G01N 21/658 (2013.01); G01N 33/54346 (2013.01); G01N 33/54373 (2013.01); G01N 2800/10 (2013.01);
Abstract

The invention relates to a SERS method for analyzing a biological sample, the method comprising the following step of: a. obtaining a biological sample which is viscous biofluid, b. depositing at least one droplet of the biological sample onto a microscope slide, and drying the droplet, c. depositing a drop of an aqueous dispersion of metallic nanoparticles above the droplet dried in step b), to have a dense distribution of nanoparticles on the surface of the dried droplet and to obtain a SERS-activated biological sample, d. drying the SERS-activated biological sample, e. irradiating the SERS-activated biological sample using a light source to obtain a SERS spectrum, and f. collecting the SERS spectrum.


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