The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2026
Filed:
Jun. 15, 2021
Adverio Pharma Gmbh, Leverkusen, DE;
Peter Fey, Wuppertal, DE;
Nadine Bremeyer, Düsseldorf, DE;
Markus Longerich, Cologne, DE;
Thomas Frenzel, Cologne, DE;
Helene Faber, Dormagen, DE;
Michal Sowa, Wuppertal, DE;
Joerg Brockob, Leverkusen, DE;
Guido Becker, Krefeld, DE;
Heike Neumann, Wuppertal, DE;
ADVERIO PHARMA GMBH, Leverkusen, DE;
Abstract
The present application relates to a novel and efficient process with high yield for preparing methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate of the formula (I) in the crystalline form of modification I, wherein the x-ray diffractogram of the compound of the formula (I) in modification exhibits peak maxima of the 2 theta angle at 5.9, 6.9, 22.7, in very high purity which is significantly more cost-effective than the process known from the art and can be performed in customary pilot- and production plant-equipment (stirred tank/devices for isolation).