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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12637455 B1

PDFFull Text
Date of Patent:
May. 26, 2026

Filed:

Mar. 25, 2021

Naphthyridine and pyrido[3,4-c]pyridazine derivatives as gabaα5 receptor modulators

Applicant:

Richter Gedeon Nyrt., Budapest, HU;

Inventors:

György Szabó, Maglód, HU;

Attila Potor, Pilis, HU;

István Vágó, Budapest, HU;

György István Túrós, Budapest, HU;

Olivér Éliás, Marcali, HU;

Gábor László Kapus, Pécel, HU;

Assignee:

Richter Gedeon Nyrt., Budapest, HU;

Attorney:

Sterne, Kessler, Goldstein & Fox P.L.L.C.

Primary Examiner:

Sun Jae Yoo

Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/404 (2006.01); A61K 31/5025 (2006.01); A61K 31/5377 (2006.01); A61P 25/00 (2006.01); A61P 25/18 (2006.01); A61P 25/28 (2006.01); C07D 401/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

The present invention provides compounds of formula (I) and/or salts thereof and/or biologically active metabolites thereof and/or prodrugs thereof and/or solvates thereof and/or hydrates thereof and/or polymorphs thereof having affinity and selectivity for the gamma-aminobutyric acid A receptor subunit alpha 5 and act as GABAα5 positive allosteric modulators, thereby useful in the treatment or prevention of diseases related to the GABAα5 receptor, process for the preparation and intermediates of the preparation process thereof, pharmaceutical compositions comprising them alone or in combination with one or more other active ingredients and their use as medicaments.

Find Patent Forward Citations

Szabó, György. (2026). Naphthyridine and pyrido[3,4-c]pyridazine derivatives as gabaα5 receptor modulators (U.S. Patent No. 12637455). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12637455

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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