The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2026
Filed:
Nov. 11, 2020
Applicant:
Duke University, Durham, NC (US);
Inventors:
Michael Rod Zalutsky, Chapel Hill, NC (US);
Ganesan Vaidyanathan, Chapel Hill, NC (US);
Darryl Lynn Mcdougald, Durham, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07B 59/00 (2006.01); A61K 47/68 (2017.01); C07F 7/22 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07B 59/00 (2013.01); A61K 47/6869 (2017.08); C07F 7/2208 (2013.01); C07K 16/3069 (2013.01); A61K 2039/505 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/77 (2013.01);
Abstract
The application is drawn to radiohalogen prosthetic moieties and precursors thereof and to radiolabeled biomolecules comprising such radiohalogen prosthetic moieties. The biomolecules have an affinity for particular types of cells and may specifically bind a certain cell, such as a cancer cell. Relevant biomolecules include antibodies, monoclonal antibodies, antibody fragments, peptides, other proteins, nanoparticles, aptamers, and pharamacological moieties used to target prostate-specific membrane antigen (PSMA).