The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2026

Filed:

Aug. 16, 2021
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Cameron Martino, La Jolla, CA (US);

Benjamin Kellman, La Jolla, CA (US);

Nathan Lewis, La Jolla, CA (US);

Robin Knight, La Jolla, CA (US);

Jeffrey D. Esko, La Jolla, CA (US);

Daniel Sandoval, La Jolla, CA (US);

Thomas Mandel Clausen, La Jolla, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/51 (2006.01); A61K 35/74 (2015.01); A61K 38/46 (2006.01); A61P 31/14 (2006.01); C12Q 1/02 (2006.01); C12Q 1/34 (2006.01); C12Q 1/527 (2006.01);
U.S. Cl.
CPC ...
A61K 38/51 (2013.01); A61K 35/74 (2013.01); A61K 38/465 (2013.01); A61P 31/14 (2018.01); C12Q 1/02 (2013.01); C12Q 1/34 (2013.01); C12Q 1/527 (2013.01); C12Y 301/06013 (2013.01); C12Y 301/06014 (2013.01); C12Y 402/02007 (2013.01);
Abstract

Methods and compositions for diagnosing, preventing or treating a viral infection in a subject comprising administering to a subject in need thereof an effective amount of a glycosidase or a sulfatase to degrade a glycan, such as heparan sulfate, to inhibit viral infection, such as COVID-19. Methods for identifying a glycosidase, a sulfatase, or a microbe associated with increased susceptibility to viral infection in a subject.


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