The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2026
Filed:
Feb. 12, 2020
Applicant:
Centre for Addiction and Mental Health, Toronto, CA;
Inventors:
Assignee:
Centre for Addiction and Mental Health, Toronto, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5517 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5517 (2013.01); A61P 25/28 (2018.01);
Abstract
The invention provides methods and related compositions for preventing neurocognitive decline associated with chronic stress, age, and neurodegenerative diseases. The methods described here are based upon the use of alpha5-GABAA receptor agonists to slow or prevent deleterious morphological changes in dendrites of the hippocampus and prefrontal cortex, which eventually manifest in functional decline and the neurocognitive deficits.