The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2026
Filed:
Mar. 26, 2020
Applicant:
United Therapeutics Corporation, Silver Spring, MD (US);
Inventor:
Martine A. Rothblatt, Silver Spring, MD (US);
Assignee:
United Therapeutics Corporation, Silver Spring, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/53 (2006.01); A61K 9/00 (2006.01); A61K 33/00 (2006.01); A61K 45/06 (2006.01); A61P 9/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/53 (2013.01); A61K 9/0075 (2013.01); A61K 9/0078 (2013.01); A61K 33/00 (2013.01); A61K 45/06 (2013.01); A61P 9/12 (2018.01); A61K 9/008 (2013.01); A61K 2300/00 (2013.01);
Abstract
The present disclosure provides compositions and methods for treating pulmonary hypertension. The compositions and methods are based on administering a NO-releasing compound, such as nitrite, to a subject in need thereof in an amount sufficient to increase the level of circulating nitric oxide (NO), a potent vasodilator, thereby reducing the subject's blood pressure and increasing blood flow.