The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2026

Filed:

Jan. 17, 2025
Applicant:

Rivo Bio, Inc., Boston, MA (US);

Inventors:

Alan C. Gibbs, Wyndmoor, PA (US);

Rebecca Aron, Brookline, MA (US);

Assignee:

Rivo Bio, Inc., Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/137 (2006.01); A61K 31/397 (2006.01); A61K 31/435 (2006.01); A61P 25/24 (2006.01); C07C 211/30 (2006.01); C07D 205/04 (2006.01); C07D 333/78 (2006.01); C07D 401/08 (2006.01); C07D 405/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/137 (2013.01); A61K 31/397 (2013.01); A61K 31/435 (2013.01); A61P 25/24 (2018.01); C07C 211/30 (2013.01); C07D 205/04 (2013.01); C07D 333/78 (2013.01); C07D 401/08 (2013.01); C07D 405/10 (2013.01);
Abstract

The present invention relates to novel chemical compounds of indane-, indene-, azaindane-, and azaindene-amines that act as 5-HT2A receptor agonists. These compounds are designed to offer improved therapeutic profiles for the treatment of a variety of neuropsychiatric, neurological, and neurodegenerative disorders. Also disclosed are methods for the synthesis and pharmaceutical use of these compounds.


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