The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2026

Filed:

Jun. 01, 2023
Applicant:

Egenesis, Inc., Cambridge, MA (US);

Inventors:

Jacob Layer, Cambridge, MA (US);

Wenning Qin, Cambridge, MA (US);

Yinan Kan, Cambridge, MA (US);

Juliet Crabtree, Cambridge, MA (US);

Michele Youd, Cambridge, MA (US);

David Heja, Cambridge, MA (US);

David Angeles Albores, Cambridge, MA (US);

Ranjith Anand, Cambridge, MA (US);

Paola Perrat, Cambridge, MA (US);

Russell Ernst, Cambridge, MA (US);

Violette Paragas, Cambridge, MA (US);

Assignee:

eGenesis, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); A01K 67/0276 (2024.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 14/745 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); A01K 67/0276 (2013.01); C07K 14/4747 (2013.01); C07K 14/70503 (2013.01); C07K 14/70596 (2013.01); C07K 14/7455 (2013.01); C12N 9/0083 (2013.01); C12Y 114/99003 (2013.01); A01K 2207/12 (2013.01); A01K 2227/108 (2013.01); A01K 2267/025 (2013.01); C12N 2830/20 (2013.01); C12N 2830/50 (2013.01);
Abstract

The present disclosure relates to cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance. In addition, the present disclosure relates to methods of making and using the cells, tissues, organs, and/or animals having one or more of the modified genes.


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