The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2026
Filed:
Jun. 25, 2021
Amgen Inc., Thousand Oaks, CA (US);
Hailing Hsu, Thousand Oaks, CA (US);
Ian Foltz, Thousand Oaks, CA (US);
Marissa Mock, Thousand Oaks, CA (US);
Victor Mitch Luna, Thousand Oaks, CA (US);
Ming Zhang, Thousand Oaks, CA (US);
Sharon Lynn Wannberg, Thousand Oaks, CA (US);
Gamze Ozlem Camdere Tapia, Thousand Oaks, CA (US);
Timothy Patrick Riley, Thousand Oaks, CA (US);
AMGEN INC., Thousand Oaks, CA (US);
Abstract
The present disclosure relates, in general, to muteins of IL-10 that are stable as monomers, antigen binding proteins that bind to TREM-1, and antigen binding proteins comprising IL-10 muteins and antigen binding moieties, e.g., anti-TREM-1 antibodies, and compositions thereof. The disclosure also provides methods of treating inflammatory disease, such as inflammatory bowel disease or ulcerative colitis, using the compositions.