The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2026

Filed:

Jun. 19, 2020
Applicant:

Endogena Therapeutics, Inc., San Francisco, CA (US);

Inventors:

Matthias Steger, Zurich, CH;

Alex Mueller, Zurich, CH;

Mauro Marigo, Zurich, CH;

Assignee:

ENDOGENA THERAPEUTICS, INC., San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/12 (2006.01); C07D 263/32 (2006.01);
U.S. Cl.
CPC ...
C07D 413/12 (2013.01); C07D 263/32 (2013.01);
Abstract

A method of treating and/or preventing disease involving retinal pigment epithelium, including administering compound of formula (I) or a pharmaceutically acceptable salt, a racemic mixture, a corresponding enantiomer or a corresponding diastereomer thereof, wherein: R, Rand Rare independently selected from the group consisting of hydrogen, fluoro, chloro, methoxy, trifluoromethyl, methyl and difluoromethoxy, whereby at least one of R, Rand Ris not hydrogen, B is selected from the group consisting of a residue of formula (II), (III), (IV), (V), (VI) and (VII) wherein, '*' denotes point of attachment to remainder of the molecule, and R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, Rare independently selected from the group consisting of hydrogen, a linear or branched alkyl having 1 to 3 carbon atoms, fluoro, chloro, bromo, methoxy, ethoxy, propoxy, trifluoromethyl and difluoromethoxy.


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