The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2026
Filed:
Jun. 05, 2020
Applicant:
Arcus Biosciences, Inc., Hayward, CA (US);
Inventors:
Manmohan Reddy Leleti, Dublin, CA (US);
Dillon Harding Miles, Berkeley, CA (US);
Brandon Reid Rosen, San Mateo, CA (US);
Ehesan Ul Sharif, Menlo Park, CA (US);
Jay Patrick Powers, Pacifica, CA (US);
Assignee:
ARCUS BIOSCIENCES, INC., Hayward, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 239/42 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 239/42 (2013.01);
Abstract
Provided herein are improved processes for preparing aminopyrimidine compounds of Formula (I). The disclosed processes advantageously proceed through a β-diketoester intermediate of Formula (A) and avoid the direct linking of a pyrimidine and phenyl moieties. The disclosed methods significantly increase yield of the desired compounds and simplifies the synthetic route.