The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2026

Filed:

Jun. 03, 2022
Applicant:

Genzyme Corporation, Cambridge, MA (US);

Inventors:

Junkai Liao, Bridgewater, NJ (US);

Mark Munson, Bridgewater, NJ (US);

Zhongli Gao, Bridgewater, NJ (US);

Gregory Hurlbut, Bridgewater, NJ (US);

Hans Peter Nestler, Bridgewater, NJ (US);

Ingrid Mechin, Bridgewater, NJ (US);

Martin Smrcina, Bridgewater, NJ (US);

Ronghua Li, Bridgewater, NJ (US);

Ryan Hartung, Bridgewater, NJ (US);

William Bock, Bridgewater, NJ (US);

Bertrand Vivet, Bridgewater, NJ (US);

Andrew Scholte, Bridgewater, NJ (US);

Assignee:

Genzyme Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/54 (2006.01); A61K 45/06 (2006.01); C07D 277/64 (2006.01); C07D 333/64 (2006.01); C07D 417/04 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 333/54 (2013.01); A61K 45/06 (2013.01); C07D 277/64 (2013.01); C07D 333/64 (2013.01); C07D 417/04 (2013.01); C07D 417/12 (2013.01);
Abstract

The present disclosure relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.


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