The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2026
Filed:
Mar. 12, 2020
Applicant:
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Inventors:
Assignee:
OTSUKA PHARMACEUTICAL CO., LTD., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07B 59/00 (2006.01); C07C 253/30 (2006.01); C07D 207/09 (2006.01); C07D 209/34 (2006.01); C07D 213/75 (2006.01); C07D 215/58 (2006.01); C07D 221/04 (2006.01); C07D 295/023 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 417/04 (2006.01); C07D 451/10 (2006.01); C07D 471/14 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); C07D 498/06 (2006.01); C07D 513/14 (2006.01); C07F 9/6558 (2006.01);
U.S. Cl.
CPC ...
C07B 59/001 (2013.01); C07C 253/30 (2013.01); C07D 207/09 (2013.01); C07D 209/34 (2013.01); C07D 213/75 (2013.01); C07D 215/58 (2013.01); C07D 221/04 (2013.01); C07D 295/023 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 417/04 (2013.01); C07D 451/10 (2013.01); C07D 471/14 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01); C07D 498/06 (2013.01); C07D 513/14 (2013.01); C07F 9/65583 (2013.01); C07B 2200/05 (2013.01);
Abstract
The present invention relates to a method of mono-deuterated-lower-alkylating the amine part in a compound having an amine protected with an aralkyl, which comprises introducing mono-deuterated lower-alkyl into the amine with a deuterated-lower-alkylating agent under neutral or basic condition, and then deprotecting the aralkyl group.