The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2026

Filed:

Oct. 14, 2021
Applicant:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Inventors:

Marc D. Breton, Charlottesville, VA (US);

Jose Garcia-Tirado, Charlottesville, VA (US);

Jenny Diaz-Castaneda, Charlottesville, VA (US);

Dayu Lv, Charlottesville, VA (US);

John Corbett, San Diego, CA (US);

Patricio Colmegna, Charlottesville, VA (US);

Assignee:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61M 5/172 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); G16H 20/17 (2018.01); G16H 20/60 (2018.01); G16H 40/67 (2018.01); G16H 50/20 (2018.01);
U.S. Cl.
CPC ...
A61M 5/1723 (2013.01); G16H 20/17 (2018.01); G16H 40/67 (2018.01); G16H 50/20 (2018.01); A61M 2230/201 (2013.01); G16H 20/60 (2018.01);
Abstract

A method, system, and computer-readable medium are provided for a dual mode Closed-Loop Control (CLC) system integrating each of (i) an adaptive, personalized Model Predictive Control (MPC) control law that modulates the control strength of insulin infusion depending on recent past control actions, glucose measurements, and their derivative(s), (ii) an automatic Bolus Priming System (BPS) that commands additional insulin injections upon the detection of enabling metabolic conditions (e.g., an unannounced meal), and (iii) a hyperglycemia mitigation system (HMS) to avoid prevailing hyperglycemia.


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