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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12629448 B1

PDFFull Text
Date of Patent:
May. 19, 2026

Filed:

Dec. 20, 2024

Preparation method for three-dimensional gelatin scaffold with interconnected pores and application thereof

Applicant:

Tianjin Hospital, Tianjin, CN;

Inventors:

Baoshan Xu, Tianjin, CN;

Tongxing Zhang, Tianjin, CN;

Tong Li, Tianjin, CN;

Zhenhua Li, Tianjin, CN;

Haifan Zhao, Tianjin, CN;

Bing Peng, Tianjin, CN;

Jianhai Wang, Tianjin, CN;

Assignee:

Tianjin Hospital, Tianjin, CN;

Attorney:
Primary Examiner:

Carlos A Azpuru

Assistant Examiner:

Casey S Hagopian

Int. Cl.
CPC ...
A61L 27/22 (2006.01); A61L 27/36 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
A61L 27/222 (2013.01); A61L 27/3604 (2013.01); A61L 27/56 (2013.01); A61L 2430/34 (2013.01);
Abstract

The present application provides a preparation method for a three-dimensional gelatin scaffold with interconnected pores and an application thereof. The preparation method includes the steps of: dissolving a pharmaceutical gelatin to obtain a gelatin solution; emulsifying the gelatin solution using an ultrasonic crusher to obtain a gelatin emulsion; pouring the gelatin emulsion into a preset mold, and freezing and curing the gelatin emulsion to obtain a cured product; performing vacuum drying of the cured product using a low-temperature freeze dryer to obtain a dried product; cross-linking and denaturing the dried product with glutaraldehyde to obtain a cross-linked product; and washing the cross-linked product several times, followed by freeze-drying to obtain a three-dimensional gelatin scaffold with interconnected pores. The three-dimensional gelatin scaffold with interconnected pores has an optimal pore size, porosity and pore size of interconnected pores, and the preparation method is applicable to industrial production.

Find Patent Forward Citations

Xu, Baoshan. (2026). Preparation method for three-dimensional gelatin scaffold with interconnected pores and application thereof (U.S. Patent No. 12629448). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12629448

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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