The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2026

Filed:

Aug. 12, 2022
Applicant:

Huashan Hospital, Fudan University, Shanghai, CN;

Inventors:

Jie Liu, Shanghai, CN;

Feifei Luo, Shanghai, CN;

Shaocong Mo, Shanghai, CN;

Huan Song, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G16H 50/70 (2018.01); G06N 20/10 (2019.01); G16B 40/30 (2019.01);
U.S. Cl.
CPC ...
G16H 50/70 (2018.01); G16B 40/30 (2019.02); G06N 20/10 (2019.01);
Abstract

A method and a system of molecular typing and subtyping classifier for immune-related diseases are provided. The method includes: conducting molecular typing via a clustering algorithm in a training set to obtain a plurality of subtypes stably appearing in the training set and a marker gene for each subtype; conducting enrichment analysis on marker genes for the plurality of subtypes, conducting immune cell infiltration evaluation on the plurality of subtypes, and dividing the plurality of subtypes into a plurality of subtype classes according to results of the analysis and the evaluation; comparing treatment response rates of different subtype classes through a comparison set to determine a subtype class to be identified; constructing a support vector machine model with feature genes screened and an optimal parameter combination; and determining whether immune-related disease data to be classified is the subtype class to be identified.


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