The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2026

Filed:

Dec. 11, 2020
Applicants:

President and Fellows of Harvard College, Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Luis Ruben Soenksen Martinez, Boston, MA (US);

Nicolaas Angenent-Mari, Somerville, MA (US);

Alexander S. Garruss, Cambridge, MA (US);

James J. Collins, Newton, MA (US);

George M. Church, Cambridge, MA (US);

Katherine Collins, Cambridge, MA (US);

Diogo M. Camacho, Cambridge, MA (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6816 (2018.01); C12N 15/10 (2006.01); C12N 15/11 (2006.01); C12Q 1/6886 (2018.01); C12Q 1/6897 (2018.01); C12Q 1/70 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6816 (2013.01); C12N 15/1089 (2013.01); C12N 15/11 (2013.01); C12Q 1/6886 (2013.01); C12Q 1/701 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6897 (2013.01); C12Q 2600/158 (2013.01);
Abstract

This disclosure provides riboregulators specific for particular viruses or for particular human transcription factors. The viral-specific riboregulators may be used to detect the presence of the particular virus, and this may enable diagnosis of an infection. The transcription factor specific riboregulators may be used to detect the presence and/or measure the level of the particular transcription factor, and this may enable diagnosis or prognosis of a particular condition such as cancer.


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