Sensor receptacle for using a conventional sensor with a single-use bioreactor while maintaining the sterility of the single-use bioreactor

Abstract

A bioreactor system () has a pre-sterilized single-use bioreactor () with a reactor wall () surrounding an interior chamber () that receives a fluid medium (M). A sensor () for detecting an analyte in the medium has a sensor housing () with an outside thread () and a sensor shaft (), a distal end portion () of which has an end face () with a region () permeable to the analyte. A sensor receptacle () connected to the reactor wall receives the sensor, to maintain the sterility of the single-use bioreactor. A circumferential flange () fixes the sensor receptacle to the reactor wall. The flange has an inside thread () that receives the outside thread. A wall () of the sensor receptacle is connected to the flange, and together with the sensor shaft, protrudes into the interior chamber, separating the sensor from the interior chamber.