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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12624173 B1

PDFFull Text
Date of Patent:
May. 12, 2026

Filed:

May. 31, 2022

Biodegradable polymeric compositions, methods of preparation and uses thereof

Applicant:

B.g. Negev Technologies and Applications Ltd., AT Ben-gurion University, Beer Sheva, IL;

Inventor:

Amnon Sintov, Omer, IL;

Assignee:

B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY, Beer Sheva, IL;

Attorneys:

Roach Brown McCarthy & Gruber, P.C.

Kevin D. McCarthy

Primary Examiner:

Daniel E Kolker

Assistant Examiner:

Julia A Rossi

Int. Cl.
CPC ...
C08J 3/14 (2006.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 9/19 (2006.01); A61K 9/51 (2006.01); A61K 9/70 (2006.01); A61K 31/047 (2006.01); A61K 31/12 (2006.01); A61K 31/46 (2006.01); A61K 38/28 (2006.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
C08J 3/14 (2013.01); A61K 9/0043 (2013.01); A61K 9/1075 (2013.01); A61K 9/19 (2013.01); A61K 9/5123 (2013.01); A61K 9/5161 (2013.01); A61K 9/5192 (2013.01); A61K 9/7007 (2013.01); A61K 31/047 (2013.01); A61K 31/12 (2013.01); A61K 31/46 (2013.01); A61K 38/28 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61K 47/64 (2017.08); C08J 2301/28 (2013.01); C08J 2303/04 (2013.01); C08J 2305/04 (2013.01);
Abstract

Disclosed herein compositions of polysaccharides chemically cross-linked by aromatic dialdehydes. The compositions may be in form of polymeric sheets for a variety of applications. Disclosed also nano-sized particles comprising the polysaccharide chemically cross-linked by aromatic dialdehydes. The nano-sized particles may further comprise lipids and surfactants. Intranasal delivery of the nano-sized particles enables delivery of biologically active agents into the brain. Topical and transdermal delivery of the nano-sized particles enables delivery of biologically active agents for treatment of systemic or dermatological disorders. Methods of manufacturing and uses of the compositions are also disclosed.

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