The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2026

Filed:

Nov. 19, 2020
Applicant:

Bmg Pharma S.p.a., Milan, IT;

Inventors:

Marco Mastrodonato, Milan, IT;

Luca Stucchi, Torviscosa, IT;

Alessandra Sechi, Torviscosa, IT;

Fabrizio Picotti, Torviscosa, IT;

Rita Gianni, Monrupino, IT;

Assignee:

BMG PHARMA S.P.A., Torviscosa, IT;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C08B 37/08 (2006.01); A61K 8/73 (2006.01); A61K 31/167 (2006.01); A61K 47/61 (2017.01); A61Q 19/00 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0072 (2013.01); A61K 8/735 (2013.01); A61K 31/167 (2013.01); A61K 47/61 (2017.08); A61Q 19/00 (2013.01);
Abstract

The present invention relates to a process for the preparation of crosslinked hyaluronic acid butyrate or crosslinked hyaluronic acid butyrate-formate or an acceptable salt thereof, wherein the process comprises the crosslinking reaction of hyaluronic acid butyrate or hyaluronic acid butyrate-formate or a pharmaceutically acceptable salt thereof in an organic solvent with a carboxyl activating reagent, characterized in that the hyaluronic acid butyrate or hyaluronic acid butyrate-formate or pharmaceutically acceptable salt thereof is a mixture of a high-molecular-weight polysaccharide and a low-molecular-weight polysaccharide.


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