The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2026

Filed:

Nov. 22, 2022
Applicant:

Korea Institute of Science and Technology, Seoul, KR;

Inventors:

Tae Song Kim, Seoul, KR;

Dong Hyun Kang, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08J 3/075 (2006.01); B01L 3/00 (2006.01); C08L 53/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502707 (2013.01); C08J 3/075 (2013.01); C08L 53/00 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/12 (2013.01); B01L 2300/16 (2013.01); C08J 2353/00 (2013.01);
Abstract

The present invention relates to a method for manufacturing a three-dimensional structure based on a block copolymer. The method comprises the steps of injecting a block copolymer (BCP) solution into each micro-well formed on the substrate and drying it to form a block copolymer layer, and applying a buffer to the block copolymer layer to hydrate the micro-well in three dimensions Forming the structure, after the three-dimensional structure is formed, injecting and curing a hydrogel solution around the three-dimensional structure may include the step of enhancing stability. In particular, the process of hydration by applying a buffer to the micro-well is performed while an electric field is applied. By controlling the concentration of the block copolymer (BCP) and the amplitude and frequency of the electric field, a three-dimensional artificial cell membrane having a desired size and shape, such as a spherical or ciliary shape and high stability (100% survival for 50 days) is manufactured can do. The present invention can be efficiently applied to various biological fields such as artificial cells, cell-mimicking biosensors, and bioreactors.


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