The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2026
Filed:
Dec. 21, 2023
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Philip Stewart Low, West Lafayette, IN (US);
Boning Zhang, West Lafayette, IN (US);
John V. Napoleon, West Lafayette, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/55 (2017.01); A61K 31/437 (2006.01); A61K 31/4535 (2006.01); A61K 31/4545 (2006.01); A61K 31/7076 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); A61K 47/62 (2017.01); A61K 47/68 (2017.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/55 (2017.08); A61K 31/437 (2013.01); A61K 31/4535 (2013.01); A61K 31/4545 (2013.01); A61K 31/7076 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4211 (2025.01); A61K 47/62 (2017.08); A61K 47/6835 (2017.08); A61K 49/0043 (2013.01); A61K 49/0052 (2013.01); A61K 2239/48 (2023.05);
Abstract
A payload of drug conjugated to a targeting ligand specifically designed to deliver to exhausted CAR T cells to rejuvenate these CAR T cells is provided herein. The targeted CAR T cells are modified with a fusion receptor which can bind to the targeting ligand and internalize the conjugated payload of drug to execute its regulatory function to exhausted CAR T cell.
Low, Philip. (2026). Rejuvenation of car t cell (U.S. Patent No. 12622973). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12622973
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile